Well located in the Setagaya Ward district of Tokyo, Real Life Meguro River is located a 10-minute walk from Ikejiri Inari Shrine, 0.7 miles from Higashiyama Kaizuka Park and a 13-minute walk from Kamimeguro Hikawa Shrine. The property is close to several well-known attractions, a 17-minute walk from Setagaya Peace Museum, 0.9 miles from Showa Women's University Hitomi Memorial Hall and an 18-minute walk from Showa Women's University Koyo Museum. Free WiFi is available and private parking can be arranged at an extra charge.

Guest rooms in the hotel are equipped with air conditioning, a seating area, a flat-screen TV with cable channels, a kitchen, a dining area, a safety deposit box and a private bathroom with a hot tub, slippers and a hairdryer. Real Life Meguro River provides certain units that include a balcony, and the rooms have an electric tea pot. At the accommodation each room includes bed linen and towels.

Popular points of interest near Real Life Meguro River include Snowdome Museum, Sugekari Park and Setagaya Park. The nearest airport is Tokyo International, 17 miles from the hotel, and the property offers a paid airport shuttle service.